[PDF] Top 20 La fisiología de la planta y la productividad del cultivo
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Characterization of a Novel Transgenic Mouse Tumor Model for Targeting HER2+ Cancer Stem Cells
... human HER2 antigen (EO771E2 cells). EO771 and EO77E2 cells were cultured in DMEM media with 10% ...EO771E2 cells were inoculated into the flank of 6-week old C57BL/6 HER2 ... See full document
10
Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer
... breast tumor cell lines [15]. We recently reported that various transgenic mouse models of breast cancer, including those shown to follow the CSC model, comprise a high fraction of BTIC ... See full document
7
Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression
... engineered mouse models (GEMs) for pancreatic cancer (PC) that recapitulates human disease progression has helped to identify new strategies to delay/inhibit PC ...pancreatic ... See full document
46
Antitumor effects of L BLP25 Antigen Specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model
... target cells overexpressing ...antigen-specific cancer immunother- apy currently under development that contains 25 amino acids from the immunogenic tandem-repeat region of MUC1 ...by targeting ... See full document
8
Mitochondrial CaMKII inhibition in airway epithelium protects against allergic asthma
... dendritic cells by bacterial chal- lenge identified a role for NLRP3/caspase-1/IL-18 in promoting allergic asthma ...epithelial cells reduced NLRP3 expression, caspase-1 activation, and mature ...in ... See full document
5
Breast cancer stem cells, cytokine networks, and the tumor microenvironment
... breast cancer, are maintained by a subpopulation of cells that display stem cell properties, mediate metastasis, and contribute to treatment ...These cancer stem cells (CSCs) are ... See full document
46
Original Article Morphological and gene-expression characterization of viable heterogeneous circulating tumor cells size-captured and cultured from triple-negative breast cancer mouse models
... breast cancer (BC) is the most com- mon invasive cancer in ...breast cancer (TNBC) [1, ...of tumor is very poor, not only because hormonal therapy and treatment with trastu- zumab are ruled ... See full document
302
Properties of internalization factors contributing to the uptake of extracellular DNA into tumor-initiating stem cells of mouse Krebs-2 cell line
... Selective targeting of TISCs by delivery of cell-killing genes carried on the plasmids is an attractive approach with a clear therapeutic ...the cells and how many native plasmid DNA molecules can be found ... See full document
6
Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells
... other cancer cell types, specific pathways that may be involved in the observed effects of Lunasin on melanoma CICs include suppression of Akt, ERK1/2, and NF-κB and activation of the tumor suppressor PTEN ... See full document
10
A mitochondrial based oncology platform for targeting cancer stem cells (CSCs) : MITO ONC RX
... By targeting the mitochondrial enzymes OXCT1 and ACAT1, we also developed new mitochondrial inhibitors that interfere with ketone metabolism, by mimicking the structure of CoA [24], (Figures 5 and ...a ... See full document
121
Characterizing the Role of the Neuropeptide Y-Y5R System in Breast Cancer
... libraries targeting 93 essential and non-essential genes, CRISPR outperformed shRNA due to the presence of more functional constructs, apparent absence of off-target effects, better consistency across cell lines ... See full document
112
Advances in Therapeutic Targeting of Cancer Stem Cells within the Tumor Microenvironment: An updated Review
... eradicate cancer include targeting the stromal cells, CSCs and immune cells within the TME [4, 5, 8, ...to tumor cells as well as strengthening the immune system is some of the ... See full document
6
A novel double-targeted nondrug delivery system for targeting cancer stem cells
... killing cancer stem cells (CSCs), the conventional chemotherapy used for cancer treatment promotes the enrichment of CSCs, which are responsible for tumor growth, metastasis, and ...by ... See full document
33
YBX1 regulates tumor growth via CDC25a pathway in human lung adenocarcinoma
... The cell cycle rhythm disorder is one of the main culprits on malignant proliferation in adenocarcinoma [8, 9]. The cell cycle program is accurately controlled by activity of phosphorylate or dephosphorylate cyclin- ... See full document
72
<p>Emerging Roles and Therapeutic Interventions of Aerobic Glycolysis in Glioma</p>
... urothelial cancer associated 1; CXCL14, C-X-C motif ligand 14; PEP, phosphoenolpyruvate; EGFR, epider- mal growth factor receptor; HSP, heat shock protein; YAP1, Yes-associated protein 1; PDH, pyranose ... See full document
7
Breast cancer, stem cells and prospects for therapy
... epithelial cells form a branching network of ducts terminating in lobules, which are in turn composed of ...epithelial cells of the ducts and lobules are ensheathed by a basal layer consisting predominantly ... See full document
7
Immuno Nanoparticles Integrated Electrical Control of Targeted Cancer Cell Development Using Whole Cell Bioelectronic Device
... of cells determine most of the cellular functions, particularly ones which occur in the cell’s ...of cancer as cancerous cells have been shown to be more electronegative than normal proliferating ... See full document
10
Cancerous stem cells: deviant stem cells with cancer-causing misbehavior
... of stem cells is their ability to self-renew and diff erentiate, investigators were prompted to explore the similarities and diff erences that exist between normal stem cell maintenance of tissues and ... See full document
5
Histopathological investigation of glioblastomas resected under bevacizumab treatment
... Cancer stem cells (CSCs) are considered to be the major source of tumor recurrence after radiation and chemotherapy, and the literature suggests that targeting CSCs is one of the ... See full document
11
Determination of HER2 status using both serum HER2 levels and circulating tumor cells in patients with recurrent breast cancer whose primary tumor was HER2 negative or of unknown HER2 status
... of tumor cells of the primary tumor have the ability to initiate metastatic growth at a different organ ...accompany tumor progres- sion and may occur before the recurrence is ...primary ... See full document
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