[PDF] Top 20 Los trastornos mentales en la atención primaria
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Alemtuzumab CARE-MS I 5-year follow-upDurable efficacy in the absence of continuous MS therapy
... From the Department of Neurology and Center for Clinical Neuroscience (E.H.), First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic; NeuroRx Research (D.L.A.), Montréal; ... See full document
6
Alemtuzumab: evidence for its potential in relapsing–remitting multiple sclerosis
... its efficacy and safety in relapsing–remitting multiple ...of alemtuzumab versus active comparator (interferon beta-1a) have been ...first-line therapy. Compared to inter- feron beta-1a, ... See full document
8
Alemtuzumab CARE-MS II 5-year follow-upEfficacy and safety findings
... comparator therapy was not con- tinued into the extension, so there is no control group for the long-term data, the clinical and imaging ben- efits observed with alemtuzumab during the exten- sion were ... See full document
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Understanding the positive benefit:risk profile of alemtuzumab in relapsing multiple sclerosis: perspectives from the Alemtuzumab Clinical Development Program
... prior therapy. Alem- tuzumab has also demonstrated durable efficacy in the absence of continuous treatment, and the majority of RRMS patients did not require retreatment following the initial ... See full document
7
Proteome analysis of excretory-secretory proteins of Entamoeba histolytica HM1:IMSS via LC–ESI–MS/MS and LC–MALDI–TOF/TOF
... for 5 min and then centrifuged at 22×g at 4 ...for 5 min at 4 °C and filtered through ...with 5 kDa molecular-weight cut off (Vivapsin, Sar- torius), and a cocktail of protease inhibitors (Roche, ... See full document
9
Minor contributions of the maxillary sinus to the air conditioning performance in macaque monkeys
... the MS, we demonstrated that the MS makes little contribution to the airflow pattern and the air-conditioning performance within the nasal cavity in ...the MS in both macaques and savanna ... See full document
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Photocontrolled DNA binding of a receptor targeted organometallic ruthenium(II) complex
... (3) (a) Aronov, O.; Horowitz, A. T.; Gabizon, A. Gibson, D. Biocon- jugate Chem. 2003, 14, 563-574. (b) Brunner, J.; Barton, J. K., Biochem- istry 2006, 45, 12295-12302. (c) Mukhopadhyay, S.; Barnes, C. M.; Haskel, A.; ... See full document
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Isolation, purification and partial characterization of a glycoside from the Jamaican ball moss plant (Tillandsia recurvata L )
... evidence of at least one likely amide to aliphatic proton correlation (Figure 3), lending credence to the MS-based hypothesis that a sialic acid moiety may be present in the molecule. Under the current sample ... See full document
9
Intensity of ICT use by managers of agricultural enterprises
... Abstract: Th e growing importance and relevance of ICT in business increases the dependence of business entities on ICTs, to which the managers of agricultural enterprises need to pay the necessary attention. Th e ... See full document
177
<p>Continuous positive airway pressure improves nocturnal polyuria in ischemic stroke patients with obstructive sleep apnea</p>
... the absence of airflow for at least 10 seconds in the presence of respiratory effort, while central apnea was defined as the absence of airflow without concurrent respira- tory ... See full document
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A multi-site, randomized controlled trial of MS INFoRm, a fatigue self-management website for persons with multiple sclerosis: rationale and study protocol
... including MS [37, 38]. The tool includes 39 questions across 5 domains: autonomy indoors, autonomy outdoors, family role, social life and relationships, and work and ... See full document
6
Early recognition of multiple sclerosis using natural language processing of the electronic health record
... the MS patients in the MS- enriched set , with clinical notes entered into the EHR up to two years prior to entry of the first ICD9[MS] code, were classified as having ...having MS, not simply ... See full document
461
A simple and rapid determination of candesartan in human plasma by LC-MS/MS
... Many options were evaluated to optimize the chromatographic conditions. Acetonitrile and methanol in combination with volatile buffers like ammonium acetate and ammonium formate and also acidic buffer like acetic acid ... See full document
21
Outcome of MS relapses in the era of disease-modifying therapy
... acute MS-relapse should not be based solely on changes in FS or EDSS but always integrate the impact upon the individual pa- tient’s daily ...of MS relapses and almost half of CIS cases in our ...the ... See full document
167
T-cell Prolymphocytic Leukemia.
... trial, patients should be offered an alemtuzumab (anti-CD52) – regimen. This was initially employed over 2 decades ago and was first used due to the strong CD52 expression on treatment-naïve T-PLL cells. Studies ... See full document
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The Effect of Hope Therapy on Hope and Perceived Stress Levels in MS Patients
... with MS and comparing the results with the results of the present study be ...health care staff to help patients cope with their problems and instill hope to patients seems to be highly ... See full document
11
A case of Alemtuzumab-induced neutropenia in multiple sclerosis in association with the expansion of large granular lymphocytes
... At the onset of neutropenia and throughout its dur- ation, clinical, serological and ultrasonic investigation did not reveal any underlying pathology (Additional file 1: Table S1). At the onset of neutropenia, peripheral ... See full document
116
VALIDATED HPTLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF EMTRICITABINE AND TENOFOVIR IN DRUG FORMULATION
... The slit dimension was kept at 5mm × 0.45mm and the scanning speed was 10mm s −1 . The source of radiation used was a deuterium lamp emitting a continuous UV spectrum between 200 and 400 nm. All determinations ... See full document
16
Proteome Analysis of Liver Cells Expressing a Full-Length Hepatitis C Virus (HCV) Replicon and Biopsy Specimens of Posttransplantation Liver from HCV-Infected Patients
... to 5; see also Table S1 in the supplemental ...flight MS (MALDI-TOF-MS) or microcap- illary high-performance liquid chromatography followed by electrospray tandem mass spectrometry ... See full document
9
THERAPEUTIC EFFICACY OF HYDROCHLOROTHIAZIDE WITH LOSARTAN AS A FIXED DOSE COMBINATION BY LC-MS/MS
... drugs decreasing the action of RAAS and ARBs. In this study we explore the pharmacokinetic study of single dose (Losartan Potassium 50 mg) of drug side by side a fixed dose combination (containing Losartan Potassium 50 ... See full document
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