[PDF] Top 20 Propuesta metodológica para la evaluación de proyectos en cinco pasos
Has 10000 "Propuesta metodológica para la evaluación de proyectos en cinco pasos" found on our website. Below are the top 20 most common "Propuesta metodológica para la evaluación de proyectos en cinco pasos".
Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination
... been previously reported in [47]. Age-matched controls (24 children, 24 adults) were selected on the basis of clinical disease (general medical and non-inflammatory neurological disorders), and not on their negative ... See full document
84
Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination
... Our study has several limitations. First, the majority of patients were children, and most of them had a benign monophasic disease course. Only very few adult patients with severe disease courses were included. Indeed, ... See full document
8
Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis
... anti-MOG antibody responses are highly specific for certain epitopes of human ...that demyelination is aug- mented in an animal model of virally induced mild demyelination if the animals are ... See full document
40
Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype
... We identified anti-MOG antibodies in a subgroup of anti- AQP4 antibody-negative NMO patients (about 25%), but not in anti-AQP4 antibody-positive patients. Interestingly, some of the MOG-seropositive ... See full document
156
Reducing Th2 inflammation through neutralizing IL-4 antibody rescues myelination in IUGR rat brain
... neutralizing antibody and first performed a Luminex assay in order to determine if the IL-4 neutralizing antibody decreased IL-4 levels in ...IL-4 antibody decreased IL-4 levels to control levels in ... See full document
8
Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund’s adjuvant
... of antibody to conformationally intact MOG expressed in myelin, marmoset CNS white matter myelin was iso- lated by homogenization and sucrose gradient centrifu- gation [22, ...mg/ml myelin was ... See full document
221
Activation of terminal components of complement in patients with Guillain Barré syndrome and other demyelinating neuropathies
... neuropathies. The presence in serum of SC5b-9, an inactive C5b-9 containing S protein, was assessed quantitatively by enzyme-linked immunosorbent assay using an antibody (Ab) to neoantigens expressed on C9 when ... See full document
73
Suppression of experimental autoimmune encephalomyelitis by interleukin-10 transduced neural stem/progenitor cells
... IL-10, a regulatory cytokine mainly produced by T- helper type 2 (Th2) cells, inhibits the activity of Th1 and Th17 cells, the production of proinflammatory cytokines, including TNFα, IL-1 and IFN-γ, and chemokines, as ... See full document
138
MRI characteristics of neuromyelitis optica spectrum disorderAn international update
... Some commonalities but also differences in clinical presentation, epidemiology, and imaging have been reported between these 2 conditions, suggesting that NMOSD may not be a homogeneous nosologic entity. In addition, ... See full document
17
Chronic relapsing inflammatory optic neuropathy (CRION): a manifestation of myelin oligodendrocyte glycoprotein antibodies
... The antibody to myelin oligodendrocyte glycoprotein (MOG-Ab) has been proposed as a new marker of in- flammatory demyelinating diseases (IDDs) of the central nervous system (CNS) [3, ...good ... See full document
11
IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis
... IgG-driven human CNS autoimmune diseases such as ...avoid antibody- mediated elimination [42] via removal of glycans neces- sary for the binding of neutralizing ... See full document
131
Antibodies to myelin oligodendrocyte glycoprotein in HIV-1 associated neurocognitive disorder: a cross-sectional cohort study
... recombinant human MOG extracel- lular Ig domain (amino acids 1-125) produced in ...secondary response to myelin debris rather than a pathogenic anti- body ... See full document
7
Spinal Cord Regeneration: Ready, Set, Nogo
... product of the suspect gene believed to code for NI-250 was exposed to IN-1 antibody. The IN-1 protein readily bound to NI-250. Additionally, we were able to isolate the cDNA coding for this protein and name it ... See full document
83
Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline
... to demyelination in the adult ...remyelination response was dominated by the dorsal (cortex-derived) ...proliferative response of dOPs was detected at 5 dpl, with differ- entiation into CC1+ dOLs and ... See full document
254
CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin
... and T cells, active degradation of myelin and damage to axons and neurons. The disease often develops from iso- lated self-limiting episodes with various neurological manifestations, including paralysis, to ... See full document
22
Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA
... two different antibodies against Fyn revealed an interaction between Fyn and Dcc in both immature (4 DIV) and mature (6 DIV) oligodendrocytes (Fig. 7A). Five minutes following application of netrin 1, an increased amount ... See full document
8
Myelin oligodendrocyte glycoprotein–specific T and B cells cooperate to induce a Devic like disease in mice
... (TCR MOG mice; also referred to as 2D2 mice) and reported that a large proportion of these mice develop spontaneous isolated optic neuritis. We have now crossed the TCR MOG mice with MOG-specific Ig heavy-chain knock-in ... See full document
17
Autoantibodies against myelin antigens in patients with neuromyelitis optica
... anti-nuclear antibody, anti-Ro/SS-A antibody, anti-scleroderma-70 antibody, anti-cardiolipin antibody, lupus anticoagulant, thyroid stimulating anti- body, anti-thyroid peroxidase ... See full document
12
Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
... HEK-293A cells (ATCC, LGC Standards GmbH, Wesel, Germany) were transiently transfected (Fugene 6 transfec- tion reagent, Roche, Mannheim, Germany) using the Vivid Colours ™ pcDNA ™ 6.2C-EmGFP-GW/TOPO plasmid (Invitrogen, ... See full document
7
MOG antibody seropositivity in a patient with encephalitis: beyond the classical syndrome
... thyroid function and antibodies, autoantibodies to synaptic receptors and neuronal cell surface proteins was also negative. The criteria for collagen diseases, vasculitis, Behçet and Hashimoto encephalopathy were not ... See full document
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