LEGISLACION MEXICANA I EL CUERPO DEL DELITO
II, LA RESPONSABILIDAD PENAL A) EN LA CONSTITUCIÓN
D) ALGUNAS CONSIDERACIONES EN TORNO A LA PRETENDIDA REFORMA DE 1997.
RESEARCH TITLE: A CASE-CONTROL STUDY OF THE PREVALENCE AND PRESENTATION OF LASSA FEVER IN FEBRILE CHILDREN WITH CONVULSIONS IN IRRUA SPECIALIST TEACHING HOSPITAL, IRRUA
PRINCIPAL INVESTIGATOR / RESEARCHER:
Dr ODIGIE C. AKHUEMOKHAN DEPARTMENT OF PAEDIATRICS
IRRUA SPECIALIST TEACHING HOSPITAL, IRRUA, EDO STATE Mobile: 08034898681, E-Mail: [email protected]
SUPERVISORS:
Prof GEORGE O. AKPEDE DEPARTMENT OF PAEDIATRICS
IRRUA SPECIALIST TEACHING HOSPITAL, IRRUA, EDO STATE
Dr OSAGIE S. DAWODU
DEPARTMENT OF PAEDIATRICS
IRRUA SPECIALIST TEACHING HOSPITAL, IRRUA, EDO STATE
STUDY LOCATION: IRRUA SPECIALIST TEACHING HOSPITAL, IRRUA, EDO STATE and THE INSTITUTE FOR LASSA FEVER RESEARCH AND CONTROL, IRRUA
The study is to determine the number of children with Lassa fever amongst children presenting with fever and convulsions. Your child/ward will not be exposed to other risks apart from routine care appropriate for his/her condition. The benefits of the study will include a better understanding of causes of fever and convulsion in children, especially the role of Lassa fever. All information given will be confidential and untraceable to you or your child. You reserve the right to withdraw at any time.
I hereby confirm that
• I have read the clinical data form for the above study or had it read to me. The content of the study, as well as the implications of my child’s participation, have been explained to me and are fully understood.
• I have had appropriate opportunity to ask questions and am fully satisfied with the responses received.
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• I understand that my participation is voluntary and that I am free to withdraw from the study at any time without giving any reasons and my decision to withdraw will not affect the care of my child. I give my full consent to have my child take part in the study.
__________________________ ________________________
RESEARCHER NAME OF PARENT / GUARDIAN __________________________ _______________________
DATE / SIGNATURE DATE / SIGNATURE
APPENDIX II
CLINICAL DATA FORM
Date (dd/mm/yy) Surname ID number/code
First name SECTION A: GENERAL INFORMATION
HOSPITAL NUMBER
SECTION B: HISTORY I
DATE (dd/mm/yy) SYMPTOMS/DURATION
Fever PAIN yes No
Sore throat yes No
Sex Age SOURCE OF REFERRAL
Self
Hospital Private Clinic
DOMICILE
State
LGA Town Village
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Muscle aches yes No
site
Headaches description yes No
onset Duration
Chest pain yes No
site
Abdominal pain yes No
site CONVULSIONS
DESCRIPTION (by parent/guardian)
Episodes Duration(min/hr) Time from last episode(min/hr) Drugs/treatment
Past history of convulsions yes No Age at onset
No of episodes
Family history of convulsions yes No father
mother Brother sister uncle aunt
Neonatal period yes No
birth asphyxia jaundice fever Convulsions Hospitalisation
yes No
Poor appetite jaundice nausea
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vomiting diarrhoea depression malaise weakness oliguria cough
Difficulty in breathing Visual problems Other 1 Other 2 Other 3
SECTION B: HISTORY II
DATE (dd/mm/yy)
Current medication/drugs
Traditional medicines specify
Family history
Recent febrile illness in other family members
Past medical problems
Previous treatment
When did they seek medical attention hospitalizations Diet/feeding
EBM
FORMULA MIXED FEEDS NUTRITIONAL SUPPLEMENTS REGULAR DIET FOR AGE
Birth history (for infants ≤ 12 months)
Maternal status
Duration of membrane rupture delivery
Vaginal C/S Gestational age Congenital anomalies
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SECTION C: PHYSICAL EXAMINATION I
DATE (dd/mm/yy)
EXAMINATION Temperature
< 3yr (rectal)
>or = 3yr (axillary) OFC
MUAC Wt Ht Lt
General appearance
Acute
Chronic Not ill
Facial puffiness Yes No
Oedema Yes No
Abnormal bleeding Yes No
Petechiae / ecchymoses Yes No
generalized Yes No
localized Yes No
Pallor Yes No
Jaundice Yes No
Dehydration mild Yes No
moderate severe
Lymph node enlargement Yes No
Skin (cold/clammy) CNS
Level of consciousness
Yes No
Immunizations
BCG
OPV0 OPV1 OPV2 OPV3
DPT1 DPT2 DPT3
HBV MMR
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Blantyre coma scale GCS
Restlessness/drowsiness/confusion Yes No
Tinnitus/hearing loss Yes No
Deep Tendon Reflex
hyporeflexia hypereflexia normoreflexia
Plantar reflex
extensor flexor normal Muscle tone
increased decreased normal side limb SECTION C: PHYSICAL EXAMINATION II
DATE (dd/mm/yy) Eyes
Conjunctivae Inflammed Uninflammed Bilateral
unilateral pupils Size
Reaction to light Yes no Fundoscopy
Papiloedema Haemorrhage
ENT
Ears Inflammed Uninflammed Throat Inflammed Uninflammed
RESPIRATORY
Respiratory Distress
Rate (/min) Percussion note
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resonant dull Stony dull
Thoracocentesis (ml) Lung exam
vesicular Crepitations
CARDIOVASCULAR Pulses
Rate (/min) Rhythm Volume Blood pressure(mmHg) Distended neck veins Gallop rhythm ABDOMEN
Ascites Yes no
Tender liver Yes no
Size
Tender spleen Yes no
Size Others
Others
Others
SECTION D: INVESTIGATIONS
DATE (dd/mm/yy)
PCV (%) WBC COUNT (/mm3)
Total WBC Neutrophils%
Lymphocytes%
Eosinophils%
Monocytes%
Platelet count
Lassa RT-PCR (blood)
POSITIVE
NEGATIVE INDETERMINATE
URINALYSIS
WBC
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Glucose bilirubin Malaria Parasite
POSITIVE
NEGATIVE
Blood culture
NEGATIVE
POSITIVE ORGANISM SENSITIVITY Blood glucose (mg/dl)
CSF
Appearance
Protein glucose WBC Total WBC Neutrophil % Lymphocytes % Gram stain Culture Sensitivity
SECTION E: TREATMENT AND OUTCOME Bacteria
Protein
Treatment a b C d e f g
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DATE (dd/mm/yy)
DEATH h
Final diagnosis OUTCOME
Full recovery Discharge Against Medical Advice Discharged with deficits COMPLICATIONS
CNS
SEIZURES DEAFNESS
AUDIOMETRY CVS
SHOCK RENAL
ARF RESPIRATORY
ARDS OTHERS