[PDF] Top 20 El análisis narrativo en la educación física y el deporte
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Categorization of multiple sclerosis relapse subtypes by B cell profiling in the blood
... antigen-specific B cells in the PBMC popu- lation permitted the identification of a B cell-dependent subtype of MS ...MOG-specific B cells in the blood and cerebro- spinal fluid (CSF) ... See full document
87
The role of microglia in multiple sclerosis
... cells/B cell) infiltrate into the CNS as a ...the blood–brain barrier and result in a peripheral immune ...cells, B cells, and macrophages migrate from the periphery into the CNS, which ... See full document
6
Cytometric profiling in various clinical forms of multiple sclerosis with respect to CD21+, CD32+, and CD35+ B and T cells
... + B cells were measured (Table ...+ B cells than on CD4 + or CD8 + T ...Other cell populations were not statistically different between MS patients and control subjects (P > ...various ... See full document
8
Restoration of regulatory B cell deficiency following alemtuzumab therapy in patients with relapsing multiple sclerosis
... peripheral blood mononuclear cells (PBMC) of 37 MS patients and 11 healthy controls ...during relapse compared to remission and HC (relapse vs remission: p = ...0.0006, relapse vs HC: p = ... See full document
15
Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis
... Percoll TM Plus (GE Healthcare) and 10 × HBSS −/− (Gibco), the cell suspension was mixed with the stock to get a 30% solution. Additionally, a 70% solution was pre- pared by diluting the stock isotonic Percoll ... See full document
14
Baseline blood immunological profiling differentiates between Her2– breast cancer molecular subtypes: implications for immunomediated mechanisms of treatment response
... nologic blood profile in TNBC patients may yield important clinical information to guide breast cancer prognosis and ...tumor subtypes, allowing future immunotherapeutic ... See full document
11
The multiple sclerosis relapse experience: patient-reported outcomes from the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry
... specific relapse symptoms, severity of symptoms, or the extent of disability or impairment of HRQoL associated with the ...report relapse occur- rence in the ...corticosteroid relapse therapy ... See full document
75
New approaches in the management of multiple sclerosis
... the blood–brain barrier (BBB), and events isolated within the ...of blood vessels of the CNS. T-cell transmigration across the BBB and further trafficking within the CNS are aided by matrix ... See full document
27
Diagnostic accuracy of blood B cell subset profiling and autoimmunity markers in Sjögren’s syndrome
... of blood B-cell subsets dur- ing pSS has previously been explored in regard to the disease ...in blood memory B cells in pSS patients may be explained by their accu- mulation within ... See full document
23
Deciphering the role of DNA methylation in multiple sclerosis: emerging issues
... whole blood (WB) cells, although no consistent DNA methylation differences between MS and controls were observed ...T cell DNA revealed strong evidence for hypermethylation in a few ... See full document
74
Is There a Link between Vitamin B and Multiple Sclerosis?
... of multiple sclerosis (MS). Interestingly, both MS and vitamin B deficiency results in severe myelin degeneration that leads to loss in neuronal signal ...vitamin B complex vary, although ... See full document
7
Hypogelsolinemia, a disorder of the extracellular actin scavenger system, in patients with multiple sclerosis
... in blood and CSF, which agrees with a study showing that a decrease of blood gelsolin level is inversely related to the intensity of systemic inflammation in patients with rheumatoid arthritis (RA) ... See full document
37
Treating primary-progressive multiple sclerosis: potential of ocrelizumab and review of B-cell therapies
... peripheral blood due to blockage of adhesion molecules that attach these cells to the marrow ...induced B-cell depletion, JCV-harboring precursor cells clonally expand and repopulate in the ... See full document
7
Impact of B cells to the pathophysiology of multiple sclerosis
... that B cells usually act as a source of both pro- and anti-inflammatory cyto- kines [48, ...activated B cells are considered potent producers of protective and patho- genic ...cytokines. B cells are ... See full document
11
Recent advances in the treatment of multiple sclerosis
... Abstract: Multiple sclerosis (MS) is a chronic inflammatory, immune-mediated, demyelinating, neurodegenerative disorder of the central nervous ...TH1 cell activity causing tissue damage by the ... See full document
12
The clinical potential of blood-proteomics in multiple sclerosis
... of multiple sclerosis (MS) remains ...regard, blood-proteomics represents a still-unexplored ...peripheral blood mononuclear cells (PBMCs) ... See full document
6
Early B-cell Factor gene association with multiple sclerosis in the Spanish population
... a B lymphocyte comprises multiple stages with sequential expression of genes participating in immunoglobulin gene rearrangements and ...signaling. B cell development depends on a number of ... See full document
6
Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages
... The etiology of MS is still unclear. Here, we briefly reviewed evidence supporting the hypothesis that HERVs could be the pathogenic factor linking an individual’s genetic makeup (and, therefore, their susceptibility to ... See full document
109
Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large b-cell lymphoma: a review of the literature
... large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin Lymphoma comprising of greater than 30% of adult non-Hodgkin ...large B lymphoid ...DLBCL subtypes; a detailed list of ... See full document
24
Specific peripheral B cell tolerance defects in patients with multiple sclerosis
... peripheral B cell tolerance check- point is common to MS, T1D, and RA, whereas central B cell toler- ance is only consistently impaired in T1D and ...autoreactive B cell clones ... See full document
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