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Synthesis and antimicrobial evaluation of urea and thiourea derivatives of sulfonic acid
... Sulfonic acid and its derivatives constitute an important class of organosulfur compounds widely used as detergents/surfactants, dyes, pharmaceuticals and acid catalyst ...Substituted ... See full document
160
Green synthesis of saccharin substituted urea and thiourea derivatives and their antimicrobial evaluation Rashmi Singh and Komal Jakhar*
... substituted urea and thiourea derivatives has been synthesized by reaction of differently substituted ureas and thioureas with saccharin under microwave irradiations using water as a non-toxic, non- ... See full document
94
SYNTHESIS, PHARMACOLOGICAL EVALUATION AND LIGAND-PROTEIN INTERACTION STUDY OF HYBRID UREA AND THIOUREA DERIVATIVES AS ANTIHYPERGLYCEMIC AGENTS
... KA. Synthesis and biological evaluation of some novel urea and thiourea derivatives of isoxazolo [4,5-d] pyridazine and structurally related thiazolo [4,5-d] pyridazine as ... See full document
30
Microwave Synthesis, Characterization and Antimicrobial Activity of Some Chromene Derivatives
... With a mixture of 5 mm 5-bromo-2- hydroxybenzaldehyde in ethanol (few ml) and 20% per mole of Ammonium acetate followed by of 2-cyclopenten-1-one (10 Mm) added and the constant stirring continued on Microwave irradiation ... See full document
5
Synthesis, characterization of 2-substituted benzimidazole derivatives and evaluation of antimicrobial activity
... stability. Benzimidazole is neither affected by concentrated sulfuric acid when heated under pressure to 270⁰C nor by vigorous treatment with hot HCl or with alkalis. Oxidation cleaves the benzene ring of ... See full document
11
SYNTHESIS, CHARACTERIZATION AND STUDY OF ANTIMICROBIAL AND ANTIFUNGAL ACTIVITIES OF SOME NOVEL PYRIMIDINE DERIVATIVES
... the synthesis of biologically active heterocyclic compounds, we developed here a synthetic pathway aimed to synthesize novel mercaptopyrimidines diazotized at 5 th position to screen them for their antibacterial ... See full document
112
SYNTHESIS AND BIOLOGICAL EVALUATION OF 1-SUBSTITUTED IMIDAZOLE DERIVATIVES
... General procedure for the synthesis of compounds (P1-P14) 9 : To a well-stirred solution of 4-(1H- imidazol-1-yl)benzoyl chloride (0.01mol) and triethylamine (0.01mol) in benzene, substituted anilines (P1-P10) and ... See full document
101
Synthesis and Characterization of New Series of Imidazolidin-2,4-Dione Derivatives and its Antimicrobial Activity
... of mannich base reaction. ¹HNMR spectral data of the compound (3a-3f) showed the absence of CH 2 N protons appeared at δ 4.17 - 4.32 regions, while N- CH-N proton appeared at δ 6.61-6.72 ppm respectively it is clearly ... See full document
39
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SOME NEW PYRAZOLE DERIVATIVES
... The Synthesis of substituted 1H-pyrazol-3- carbohydrazide hydrazone 5a-c is outlined in Scheme ...acetic acid to give the corresponding hydrazones 5 (Scheme ... See full document
83
Synthesis, characterization and In vitro antimicrobial evaluation of novel pyrazolothiazol-4(5H)-one derivatives
... for synthesis of compounds (3a‑3j) was outlined in Scheme 1 and the physicochemical characterization is given in Table ...For synthesis of chalcones (1a‑1j) a suspension of aromatic ketone (40 mmol) and ... See full document
6
Synthesis and Antibacterial Evaluation of Some Novel Chalcones and their Derivatives
... Compound (6a) (0.01 mol) was dissolved in glacial acetic acid (25 ml) and hydrazine hydrate (0.01 mol) was added to it and refluxed for 6 hrs. the reaction mixture was then cooled, poured into crushed ice and ... See full document
22
Synthesis and antimicrobial activity of 9-o-substituted palmatine derivatives
... their antimicrobial activity in vitro to evaluate structure-activity ...palmatine derivatives exhibit varying degrees of antimicrobial ...bacteria. Antimicrobial activities of compounds (5a-e) ... See full document
35
Synthesis of Thiazole and Oxazole Derivatives by Organic Clay as a Novel Method and their Biological Evaluation
... of synthesis of 1, 3-thiazole involves reaction of dimethyl acetylene dicarboxylate (DMAD) with esters and amides of dithiocarboxylic acids are well known methods for preparation of five membered S, and S, ... See full document
35
Volumetric and Ultrasonic Velocity Studies of Urea and Thiourea in Aqueous Solution
... of urea, thiourea molecules results of a positive volume change & (ii) the interactions between water and water decreases with increase in temperature giving rise a very small negative change in ... See full document
31
Synthesis and antimicrobial evaluation of 5-iodopyrimidine analogs
... 4-Substituted-5-iodo-2-benzylthiopyrimidines were prepared effi ciently in three steps. 2-Benzylthiopyrimidine on iodination in presence of base gave 5-iodo-2-benzylthiopyrimidine (1), which on chlorination with excess ... See full document
8
Keywords Index
... Benzimidazoles Phospho Sulfonic Acid Catalyzed Synthesis of Benzimidazole, Benzoxazole and Quinoxaline Derivatives under Green Solvent at Ambient Temperature. 1 51-63[r] ... See full document
21
Synthesis, Biological Evaluation and Molecular Docking Studies of Novel 1,8-Naphthyridine-3-carboxylic Acid Derivatives as Potential Antimicrobial Agents (Part-1)
... 1,8-naphthyridine derivatives (4a-5b2) and to support their in vitro antimicrobial ...for antimicrobial therapy is DNA ...of antimicrobial agents act through inhibiting DNA ... See full document
6
Solid support synthesis of thiazolo pyrazoline derivatives and evaluation of their antimicrobial activities
... Heterocyclic compounds include many of the biochemical materials essential for life; e.g. vitamins, hormones, nucleic acids, that carry genetic information and control inheritance. Modern society is dependent on ... See full document
15
SYNTHESIS AND ANTIBACTERIAL EVALUATION OF SOME NEW COUMARIN DERIVATIVES OF PHARMACEUTICAL INTEREST
... coumarin derivatives were prepared by condensation of resorcinol and ethyl aceto acetate followed by sulfonation with chlorosulphonic acid and amination with various water soluble primary amines ... See full document
26
Synthesis, Identification, Theoretical And Experimental Studies For Carbon Steel Corrosion Inhibition in Sea Water for New Urea and Thiourea Derivatives linkage to 5 Nitro Isatin Moiety
... includes synthesis of some new heterocyclic derivatives of 5-Nitroisatin namely 5-Nitro-3-(Ethyl imino acetate)-2-oxo indole (1), 5-Nitro-3-[(imino Aceto) urea]-2-oxo indole (2), 5-Nitro-3-[(imino ... See full document
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