[PDF] Top 20 Emmanuel, Levinas. Dios La Muerte y El Tiempo
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A role for human brain pericytes in neuroinflammation
... The role of IP-10 has been discussed; how- ever, CXCL9 and CXCL11 are also important in peripher- ally mediated-CNS inflammation ...Rat pericytes have shown the ability to express major histo- compatibility ... See full document
43
Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain
... important role in micro- glial activation and neuroinflammation [8–10, ...and neuroinflammation is involved in ethanol neurotoxicity, we could not rule out the possibility of ethanol directly killing ... See full document
59
Role of neuroinflammation in ischemic stroke
... and neuroinflammation in the brain that results from thrombotic ...blockage. Neuroinflammation occurs initially depending on activated resident microglia that has the same function as the ...injured ... See full document
300
Viral infection and neurological disorders—potential role of extracellular nucleotides in neuroinflammation
... to brain lesion areas and devour potential invaders or degenerated ...pivotal role in neuroinflammation, releasing several pro-inflam- matory cytokines and chemokines, which further recruit more ... See full document
173
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
... termed neuroinflammation, and of leukocyte recruitment to the ...acute brain injury, where it has been ascribed potential roles in repair as well as in exacerbation of ...IL-1's role in chronic ... See full document
12
Role of neuroinflammation in neurodegeneration: new insights
... AD brain, including macromolecules from Candida glabrata, Penicillium notatum, and ...many brain regions including the frontal cortex, hippocampus, and the blood vessels of the CNS, with mixed-fungal ... See full document
8
Microglia and astroglia: the role of neuroinflammation in lead toxicity and neuronal injury in the brain
... the brain. Although lead is believed to transport into the brain through the blood‑brain barrier (BBB) and cause direct neuronal injury, growing data have shown that lead exposure could induce ... See full document
342
The role of neuroinflammation in juvenile bipolar disorder
... There are preliminary findings indicating that a potential relationship exists between inflammatory process and juvenile BD, but evidences are insufficient to support the causality. Adequately powered and prospective ... See full document
38
Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice
... Trial-dependent learning was assessed using a modified protocol. Search-to-platform area determines the degree of reliance on spatial vs . non-spatial strategies. Cued tri- als determine whether performance factors that ... See full document
7
Unique and shared inflammatory profiles of human brain endothelia and pericytes
... the brain, microglia and astrocytes are the most com- monly studied neuroinflammatory cell types; however, blood vessels are another important site of cerebral inflam- mation ...the brain than in other ... See full document
27
Interferon-γ blocks signalling through PDGFRβ in human brain pericytes
... of brain microvasculature and as such play an integral role in CNS homeostasis and BBB function ...ence brain disease (reviewed [16, ...identified brain pericytes as active partici- ... See full document
164
Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro
... the brain [41-45]. Previously, we demonstrated that detachment of brain pericytes from the basal lamina is related to disruption of the BBB in LPS-injected mice ...the brain [48,49], are ... See full document
5
Pericytes and Neurovascular Function in the Healthy and Diseased Brain
... and human studies have shown that pericyte loss occurs in AD (Sagare et ...2013). Pericytes can endocytose perivascular debris, giving them a vital role in the clearance of molecules such as A β (Ma ... See full document
52
Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus
... and pericytes. Cerebral vascular pericytes (CNS peri- cytes) have been shown to enhance TJ barrier function, stimulate expression of TJ proteins and reduce the para- cellular permeability of the capillary ... See full document
15
The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer’s disease
... key role in the pathogenesis of sporadic Alzheimer ’ s disease ...the role of A β 34 as a marker for amyloid clearance in AD, we performed a systematic and comprehensive analysis of A β 34 immunoreactivity ... See full document
23
Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D
... BC1 [25] and BC1-GFP [26] hiPSC lines were maintained and differentiated to dhBMEC as previously described [27, 28] with minor modifications. All materials were purchased from Thermo Fisher Scientific unless other- wise ... See full document
8
Targeting pericytes for neurovascular regeneration
... the brain [7, 50]. Some authorities showed the critical role of PDGFRβ signaling in brain ...of pericytes around ...in pericytes numbers is observable with the emergence of vasodilation ... See full document
7
Dysregulation of sonic hedgehog pathway and pericytes in the brain after lentiviral infection
... A total of 14 adult male rhesus macaques (Macaca mulatta) were used in this study. All procedures of this study were approved by the Tulane University Institu- tional Animal Care and Use Committee (IACUC), and were ... See full document
24
Azadirachta indica ethanolic extract protects neurons from apoptosis and mitigates brain swelling in experimental cerebral malaria
... the brain parenchyma. Besides, considering that brain oedema is a major causative of the inflammatory response in the brain parenchyma (through infiltrating danger or pathogen-associated molecules ... See full document
10
Effects of methylprednisolone on blood-brain barrier and cerebral inflammation in cardiac surgery—a randomized trial
... A lumbar puncture for quantitative analysis of CSF biomarkers was performed the day before surgery and ap- proximately 24 h after surgery. We used a 27-G Whitacre spinal needle (Becton Dickinson S.A. S. Agustin del ... See full document
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