[PDF] Top 20 Hallmarks of Cancer the Next Generation 2011 (1)
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Pulmonary manifestations in Behçet disease: impaired natural killer cells activity
... and activity are a consequence of a defective differenti- ation of hematopoietic stem cells into NK cells, as re- cently described by Park et ...NK cells and dendritic cells (DCs) or T ... See full document
8
NOD2 is highly expressed in Behçet disease with pulmonary manifestations
... BAL cells were analyzed for expression of NOD1 and NOD2 proteins on a Coulter Epics XL flow cytometer (Beckman Coulter, INSERM 354, Paris, France) and gated based on forward and side scatter ...pAb. Cells ... See full document
5
Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis
... iNKT cells in SSc patients. In this study, we demonstrate that iNKT cells are significantly reduced in the peripheral blood of patients with SSc compared to healthy ...between disease or ... See full document
10
Original Article Compromised natural killer cells in pulmonary embolism
... with pulmonary hypertension and T cell immune dysfunction/disorder ...cell activity con- tribute to the onset of ...NK cells interact with virus to promote the occurrence of VTE remain largely ... See full document
199
Prevalence of hepatopulmonary syndrome in patients with cirrhosis of liver.
... Out of 40 patients in our study, HPS was identified in 4 patients (10%). All 4 patients had hypoxemia (PaO2 <70 mm Hg) and intra pulmonary shunting as established by contrast echo. They all had varices ... See full document
20
Novel aspects of pathogenesis and regeneration mechanisms in COPD
... stem cells) are recruited from circulation when ...progenitor cells in the circulation and locally (fine red arrow). Inflammatory cells (eg, neutrophils, dendritic cells, ... See full document
11
Natural Killer Cell Immunodeficiency in Siblings: Defective Killing in the Absence of Natural Killer Cytotoxic Factor Activity in Natural Killer and Lymphokine-Activated Killer Cytotoxicities
... Natural killer cells play important roles in the defense against tumor growth and viral infections.’ In the cytolytic event, natural killer cells first nec- ognize and bind to a target c[r] ... See full document
8
Activation of Natural Killer Cells by Newcastle Disease Virus Hemagglutinin-Neuraminidase
... If NDV envelope proteins directly or indirectly trigger NK cells through NKp44 and NKp46, one would expect that the enhanced lysis of NDV-infected cells can be blocked by the respective antibodies. Indeed, ... See full document
118
Comparison of Lymphocyte Number and Their Subsets in Patients with Diabetes Mellitus Type II,Tuberculosis and Concomitant TB and Diabetes
... None of our cases had congenital immunodeficiency, cirrhosis, collagen vascular disease, renal failure, malnutrition, cancer, and other immunocompromising disease. Serologic tests for HIV were done for all ... See full document
12
Biomarkers in immune checkpoint inhibition therapy for cancer patients: what is the role of lymphocyte subsets and PD1/PD-L1?
... bright, natural killer; CD56 dim NK: cluster of differentiation-56 dim, natural killer; CD8+ cells: cluster of differentiation-8 positive cells; CD80: cluster of ... See full document
123
The Challenge of Treating Pulmonary Vasculitis in Behçet Disease: Two Pediatric Cases
... Behçet disease (BD) is a multisystemic autoinflammatory disease of unknown etiology characterized by recurrent oral and genital ulcerations, uveitis, and skin lesions, first described by Hulusi ... See full document
5
The role of nonspecific cytotoxic cells and cytokine production in the pathogenesis of human intestinal diseases
... General Introduction 1.1 Characteristics of natural killer and killer cells 1 1.2 Killer cells and antibody-dependent cellular cytotoxicity 6 1.3 The origin and differentiation of natura[r] ... See full document
6
Chest HRCT findings in patients with primary Sjögren’s syndrome
... conclusion, pulmonary involvement in pSS is com- mon and occurs in around 30% of ...of pulmonary findings, even if the changes are not very ...pSS activity, because a factor or factors predisposing ... See full document
39
Natural Killer Cell Lymphoma in a Pediatric Patient With Inflammatory Bowel Disease
... A colonoscopy revealed colitis with dis- continuous ulcers. The terminal ileum appeared erythematous and hemor- rhagic. Colonic biopsy specimens re- vealed diffuse eosinophilic colitis with- out granulomas or crypt ... See full document
70
Natural killer cells and regulatory T cells in early pregnancy loss
... these cells become detrimental to fetal ...Th17 cells in circulation and decidua (Sasaki et ...dysregulation, impaired antigen education, or microbial infection and inflammation ... See full document
18
Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal Associated Invariant T Cells in Children and Adults with Coeliac Disease
... T cells, evidence points toward an immunoregulatory role for Vδ1 cells ...Vδ1 cells expand in the coeliac gut in response to signals resulting from epithelial cell damage, such as elevated MICA/B ... See full document
162
Impaired culture generated cytotoxicity with preservation of spontaneous natural killer cell activity in cartilage hair hypoplasia
... phenotype (OKM1+ OKT3- Fc gamma + low-affinity E+), and a significant decrease in thymic derived OKT3+ cytolytic T cell sub-populations in CHH individuals. Therefore, an intact cellular cytotoxic effector mechanism has ... See full document
198
Adult cancer related hemophagocytic lymphohistiocytosis – a challenging diagnosis: a case report
... Another major problem is the lack of effective therapy. Hurdles to therapy initiation, similar to our case report, include: (a) delayed recognition of HLH, (b) advanced stage of underlying disease, and (c) ... See full document
12
Anti cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells
... (Treg) cells are required for suppression of the innate anti-tumor immunity of NK and NKT cells [27, ...NKT cells can inhibit the development of Treg cells via IFN-γ production [29, ...NKT ... See full document
23
Natural killer cells and autoimmunity
... NK cells appear to participate in regulating T and B cell-mediated autoimmune ...NK cells perform this potential immunoregulatory ...other cells, activating macro- phages, or supporting the ... See full document
15
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