[PDF] Top 20 El reglamento europeo de protección de datos personales y el derecho al olvido
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Intermittent Hypoxia Alters Metabolic and Cardiovascular Neural Pathways
... When leptin was first discovered in 1994, it was believed the satiety- inducing hormone would act to resolve positive body energy balance syndromes like obesity. However, the finding of hyperleptinemia, as opposed to ... See full document
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Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome
... OSA is marked by changes in oxygen and carbon dioxide-inspired concentrations, which impact the gut microbial community (2). Since the gut microbiota plays a key role in the metabolism of dietary precursors, including ... See full document
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Possible Hypoxia Signaling Induced Alteration of Glucose Homeostasis in Rats Exposed to Chronic Intermittent Hypoxia - Role of Antioxidant (Vitamin C) and Ca2+ Channel Blocker (Cilnidipine)
... of hypoxia on the physiological system is controlled by hypoxia inducible factor- 1 ( HIF- 1 ) ...Chronic intermittent hypoxia is commonly seen in obstructive sleep ...with ... See full document
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Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-β1
... Background: Secretory leukocyte protease inhibitor (SLPI) is a protein with anti-protease and antimicrobial properties that is constitutively secreted from the airway epithelium. The importance of maintaining a balance ... See full document
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Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes
... significant metabolic alterations during differentiation and ...the metabolic changes accompanying maturation of hPSC-CMs may prove useful in identifying new strategies to expedite hPSC-CM maturation and ... See full document
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Defining the Metabolic Pathways and Host Derived Carbon Substrates Required for Francisella tularensis Intracellular Growth
... fundamental metabolic pathway that oxidizes carbohydrates to generate energy and provide precursor metabolites for other biosynthetic ...essential metabolic intermediates when glucose concentrations are ... See full document
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Atrial Fibrillation Promotion by Intermittent Hypoxia in the Rat
... of hypoxia alternated with 120-second cycles of normoxia, resulting in exposure of rats to 18 events per hour, thereby emulating a moderate form of OSA based on the AHI (AASM Task force, ...of hypoxia, ... See full document
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Increased Expression of Frontotemporal Dementia Risk Factor Tmem106b Alters Lysosomal and Autophagosomal Pathways
... death pathways responsible for the observed cytotoxicity have been ...death pathways do not play a major role in the observed ...biosynthetic pathways and cellular starvation, which may ultimately ... See full document
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Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia
... astrocytic hypoxia triggers neuronal anaerobic metabolism as manifested by the low lactate flux ...astrocytic hypoxia in the presence of neurons, which can work as a metabolic support for astro- ... See full document
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Original Article Acute exposure to hypobaric hypoxia upregulates the expression of hypoxia-inducible factor-1α and vascular endothelial growth factor
... [4]. Hypoxia stimulates the expression of both VEGF and its receptors in human endothelial cells ...alveolar hypoxia, indicating the association of VEGF with the pathogenesis of high-altitude cerebral ... See full document
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The conundrum of using hyperoxia in COVID-19 treatment strategies: may intermittent therapeutic hyperoxia play a helpful role in the expression of the surface receptors ACE2 and Furin in lung tissue via triggering of HIF-1α?
... patient’s hypoxia in the course of severe corona virus disease 2019 (COVID-19) ...regulating cardiovascular and respiratory homeostasis as well as reactive oxygen species (ROS)-production via oxidative ... See full document
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Switching off malignant mesothelioma : exploiting the hypoxic microenvironment
... A tumor suppressor gene most commonly deleted or mutated in mesotheliomas (~60% of cases) is BRCA1 associated protein-1 (BAP1), a C-terminal family of deubiquitinating enzymes (DUBs) linked to DNA damage repair ... See full document
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Ontology-based metabolic pathway prediction using saccharomyces cerevisiae data from genbank, ecocyc and kegg
... This research focuses on metabolic pathway prediction for Saccharomyces cerevisiae (S.cerevisiae). The data is already background-corrected and based on in vitro experiments, and these problems are not the focus ... See full document
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An Investigation into the Effects of Intermittent Hypoxia on Patients with Essential Hypertension.
... Hypoxicator was gradually lowered during the 4-week course of hypoxia in a step-wise fashion in accordance with the manufacturer’s recommendations. These recommendations were developed by BiomedTech (17 Roberna ... See full document
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Cardiovascular and metabolic responses to isometric exercise of athletes and non athletes
... Cardiovascular and metabolic responses to isometric exercise of athletes and non athletes Med J Malaysia Vol XXXV No 1, September 1980 CARDIOVASCULAR AND METABOLIC RESPONSES TO ISOMETRIC EXERCISE OF A[.] ... See full document
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Intermittent Hypoxia Affects Leptin and Leptin Receptor Signaling in the Rat Carotid Body
... 4 Effect of Chronic Intermittent Hypoxia on Leptin and Leptin Receptor Protein Expression in the Carotid Body ..... vii.[r] ... See full document
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Hypoxia and oxidative stress in breast cancer Hypoxia signalling pathways
... The HIF system has a central role in physiological adapta- tion to hypoxia, and is frequently activated in tumours. Activation may occur simply as an expected consequence of microenvironmental hypoxia. ... See full document
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Mechanism of Effect of Hypoxia on Renal Water Excretion
... antidiuresis, hypoxia was induced in hypophysectomized animals. The effect of hypoxia on CO, MAP, GFR, SV, and renal blood flow in hypophysectomized animals was the same as in intact ...however, ... See full document
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Distinct metabolic adjustments arise from acclimation to constant hypoxia and intermittent hypoxia in estuarine killifish (Fundulus heteroclitus)
... during hypoxia – ...acute hypoxia group, and that also drove significant or marginally significant main effects of treatment and time (Table ...acute hypoxia treatment group, and these increased ... See full document
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Original Article Relationship of learning and memory impairment in chronic intermittent hypoxic rats with hippocampus ERK activation and microtubule-associated protein 2 expression
... in intermittent hypoxia group, with time prolonged, hypoxia MAP-2 expression decreased, consistent with the trend of rat behavior changes, suggesting that long-term intermittent hypoxia ... See full document
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