specifications Course
University : Minia Faculty : Pharmacy
Department : Clinical pharmacy 1- Administrative Information Course Title:
Clinical Pharmacokinetics
Code:
PP 907
Academic Year/level:
9
thsemester Department(s) offering the
course : Clinical pharmacy
Lecture: 2hrs/week ( x12week= 24hrs/semester) Tutorial : …………
Practical: 2 hrs/week ( x12week~24hrs/year) Total : 48 hr/year
2- Aims (Module purpose)
Understanding clinical pharmacy and pharmacokinetic tasks and Principles of drug distribution absorption elimination3- Overall aims of Course:
A- Knowledge and Understanding
A1 -
Memorize Principles of clinical pharmacokinetics with applications in therapeutic drug monitoring, dosemodification and bioequivalence studies.
A2 – Gaining the principles of drug distribution absorption elimination
.
2
B- Intellectual Skills:
B1- Apply various principles to determine the characteristics of biopharmaceutical products.B2-To acquire the ability to communicate with patient in community pharmacy.
B3- To be able to apply pharmacokinetic calculation to find different pharmacokinetic parameter such as volume of distribution ,clearance and half life time.
B4-To get the ability to use pharmaceutical calculation in special patient population such as geriatrics ,renal disease and hepatic disease .
C- Professional and Practical Skills:
C1-
To acquire the clinical pharmacist profile for handling IV admixture, calculation of amount of energy needed and the sources of TPNC2- To understand the drug monitoring for narrow therapeutic index drugs such as digoxin, phention, methotrexate & aminoglycotide antibiotics
D- General and transferable skills:
D1-
Gain the skills necessary for data collection, administration and communication.4- Course Contents:
Lecture No hrs/w Practical
hours Lecture
hours Topic
2hrs/w 2 hrs
2 hrs Introduction to Clinical Pharmacokinetics
2hrs/w 2 hrs
2 hrs Distribution of drugs
2hrs/w 2 hrs
2 hrs Elimination of drugs
2hrs/w 2 hrs
2 hrs Extravascular dosage forms
2hrs/w 2 hrs
2 hrs I.V infusion
2hrs/w 2 hrs
2 hrs Multiple dosage regimen
2hrs/w 2 hrs
2 hrs Therapeutic drug monitoring (TDM)
2hrs/w 2 hrs
2 hrs Continue TDM+ drug 1
2hrs/w 2 hrs
2 hrs Drug 2+Drug 3
2hrs/w 2 hrs
2 hrs Drug 4
2hrs/w 2 hrs
2 hrs Drug 5
2hrs/w 2 hrs
2 hrs Dosage adjustment in renal and hepatic
dysfunction
Matrix I- Coverage of the course ILOs by different topics
general and transferable -
D
s
ll ski C- Professional and practical
skills:
B- Intellectual skills:
Knowledge and -
A
Understanding
Topics
C2 D1 B4 C1
B3 B2 B1 A2 A1
●
●
●
●
● Introduction to
Clinical
Pharmacokinetics
●
● ● Distribution of ●
drugs
●
● ● Elimination of ●
drugs
● ●
●
● ● Extravascular ●
dosage forms
● ●
● I.V infusion
● Multiple dosage ●
regimen
● ●
● ● Therapeutic drug ●
monitoring (TDM)
● ● digoxin
● ●
● ● Theophylline
●
● ●
● Aminoglycoside
● ● Carbamazepine
● Methotrexate ●
●
● Dosage adjustment in renal and hepatic dysfunction 5- Teaching and Learning
Methods:
Lecture: Computer, data show, white board, marker
Practical: White board, marker, laboratory chemicals, laboratory glassware,
4
Matrix II- Coverage of the course ILOs by different learning methods
s
general and transferable skill -
C- Professional and D practical skills:
B- Intellectual skills:
- A Knowledge
and Understandi
ng
Topics
C2 D1 B4 C1
B3 B2 B1 A2 A1
●
●
●
● ● lectures ●
● ●
●
● ● Practical ●
lessons
6- Teaching and Learning Methods:
to Students with Limited Capacity
There is no current methods used for student with limited capacity
7- Student Assessment:
Student Assessment Methods:
7.1 Written examination to assess the ability of student to understand the theoretical courses.
7.2 Oral examination to assess the ability of student to explain and solve problems.
7.3 Practical examination to assess the ability of student to deal with practical problems
Matrix III- Measuring the achievement of the course ILOs by different assessment methods
s
general and transferable skill -
C- Professional and D practical skills:
B- Intellectual skills:
- A Knowledge
and Understandi
ng
Topics
D1 C2
C1 B4
B3 B2 B1 A2 A1
●
●
●
● ● Written ●
● ●
● ● Oral ●
●
●
● Practical ●
Weighting of Assessment:
First term written exam First term practical exam.
Periodical term oral exam. 10%
Final term written exam. 50%
Final term practical exam. 25%
Final term oral exam. 15%
Total 100%
- List of References:
A- Course Notes Notes prepared by staff members of clinical pharmacy department, faculty of pharmacy, Minia University
B- Essential Books:
Gibaldi, biopharmaceutics & pharmacokinetics
C- Recommended Books:
Pharmacy Practice Edited by Kevin M.G.Taylor
D- Periodicals, Web sites, etc.
www.gale.com
Course Coordinator: Head of Department:
