[PDF] Top 20 Laicidad de las instituciones, sociedad multicultural y religiones
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Heterogeneity of colon cancer: from bench to bedside
... proceed from the proximal to the distal ...of colon cancers arising from the diverse sides of the colon–rectum as well as for the sensitivity to the therapy, including ...right colon ... See full document
23
Evaluating genomic tests from bench to bedside: a practical framework
... for colon cancer, for example, the initial test performance in Phase 1 would establish the assay's ability to differentiate known cases from ...colorectal cancer screening, which allows ... See full document
19
Bench to bedside review: Metabolism and nutrition
... AKI and critical illness are characterized by a catabolic state, insulin resistance, and altered carbohydrate and glucose metabolism. These changes are provoked by counter- regulatory hormones, acidosis, and cytokines. ... See full document
54
Prognostic significance of c KIT in vulvar cancer: bringing this molecular marker from bench to bedside
... Proto-oncogene c-KIT encoded tyrosine kinase appears to have an important role in carcinogenesis of various tumors, including gastrointestinal stromal tu- mors (GIST), melanomas, seminomas, glioblastomas, breast ... See full document
15
Bench to bedside review: Cytopathic hypoxia
... Tissue hypoxia is an expected correlate of any of the three classical causes of impaired cellular aerobic metabolism iden- tified by Barcroft more than 75 years ago [8]. Therefore, when the delivery of O 2 decreases on ... See full document
31
Bench to bedside review: Lactate and the kidney
... clear from the evidence presented that the kidney is a major organ for lactate disposal and that such disposal only ceases under conditions of extreme (90%) decreases in renal ...differs from the medulla to ... See full document
133
Bench to bedside review: Permissive hypercapnia
... Hypercapnic acidosis appears to exert protective effects on the myocardium. In the isolated heart, reperfusion with a hypercapnic acidotic perfusate for a short period potentiates recovery of myocardial function ... See full document
70
Bench to bedside review of myositis autoantibodies
... autoantibodies, from the molecular characterization and biological significance to target antigens, from the detection tools, with a special focus on immunofluorescence patterns on HEp-2 cells, to their ... See full document
94
Bench to bedside review: Sepsis from the redox point of view
... Pro-oxidative and pro-infl ammatory events in the plasma have a strong impact on the intracellular milieu. H 2 O 2 causes a cascade of intracellular events resulting in the liberation of NF-κB from its inhibitor ... See full document
94
The role of cognitive activity in cognition protection: from Bedside to Bench
... Evidence from neuroimaging and animal research suggested that transfer effect could be maxi- mized when tasks are designed to stimulate common brain regions ... See full document
8
Cardiovascular disease in HIV patients: from bench to bedside and backwards
... release from sanctuary sites) persists along with immune ...arises from different mechanisms including (1) the evolving HIV production (if not HIV replication); (2) the co-pathogen load of cytomegalo- virus ... See full document
5
Circulating microRNAs in malaria infection: bench to bedside
... Kirschner et al. [38] described haemolysis of cells related to increasing of miRNAs level, which led to false negative findings to evaluate the levels of red blood cell- derived miRNAs. These effects were detectable in ... See full document
8
<p>The Role of Brain Derived Neurotrophic Factor in HIV-Associated Neurocognitive Disorder: From the Bench-Top to the Bedside</p>
... Glycoprotein protein 120 (gp120), a viral envelope gly- coprotein, evokes neuronal toxicity and reduction of BDNF levels in the dorsal striatum in rodent models of HAND. 11 This reduction in BDNF levels causes synaptic ... See full document
5
Bench to bedside review: Sepsis is a disease of the microcirculation
... light from the tissues. Contrast is obtained from the absorption of linearly polarized light by the haemoglobin in the ...the bedside for humans in the visualization of unique in vivo images of the ... See full document
105
From bench to bedside, work in cell based myocardial regeneration therapy
... sorting from mice constitutively expressing enhanced green fluores- cent protein (EGFP), and transplanted these cells into an infarcted ...cells from Rosa26 mice that constitutively expressed beta- ... See full document
524
Bench to bedside review: Recruitment and recruiting maneuvers
... Animal and clinical studies have described diverse methods for recruiting the lung. A sustained high-pressure inflation uses pressures from 35 to 50 cmH 2 O for a duration of 20–40 s [22,27,29]. Pressure may need ... See full document
144
Bench to bedside: A role for erythropoietin in sepsis
... accrue from the administration of EPO within 24 hours of the onset of sepsis and organ ...guided from clinical studies where ranges between 150 and 600 IU/kg have been used ... See full document
13
Bench to bedside review: Oxygen as a drug
... during hyperoxic exposures and that hyperoxic vaso- constriction may resume after correction of the regional hypoxia. Furthermore, in a severe rat model of hemorrhagic shock, we have shown that normobaric hyperoxia ... See full document
61
Bench to bedside review: Carbon dioxide
... Th e importance and complexity of inter-relationships between alterations in systemic CO 2 tension and critical illness states is increasingly appreciated. Ventilator strategies involving hypercapnia are widely utilized ... See full document
66
Nanotherapeutics in the EU: an overview on current state and future directions
... translation from bench to ...tion from undesired nanostructures (eg, by products and starting materials); 3) scalability issues; 4) enhancing the production rate; 5) reproducibility from batch ... See full document
5
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